Molecular Basis of Inheritance — Important Questions
ICSE · Class 12 · Biology
130 important questions from Molecular Basis of Inheritance for ICSE Class 12 Biology, with answers. Written for the board exams 2027.
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Important Questions from Molecular Basis of Inheritance
Who proposed the double helix model of DNA?
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Watson and Crick
Watson and Crick proposed the double helix model in 1953, based on X-ray crystallography data from Rosalind Franklin and Maurice Wilkins. They shared the Nobel Prize in 1962.
In DNA, which base pairs with Adenine?
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Thymine
In DNA, Adenine pairs with Thymine via 2 hydrogen bonds (A≡T). Guanine pairs with Cytosine via 3 hydrogen bonds (G≡C). In RNA, Uracil replaces Thymine.
DNA replication in living organisms is:
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Semiconservative
DNA replication is semiconservative — each new double helix contains one original parental strand and one newly synthesised strand. This was proved by Meselson and Stahl (1958).
What is the central dogma of molecular biology?
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DNA → RNA → Protein
The central dogma states: DNA is transcribed to mRNA, which is translated into protein. Information flows from DNA to RNA to protein.
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