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Chapter 5 of 15
Important Questions

Molecular Basis of Inheritance

ICSE · Class 12 · Biology

Most important questions from Molecular Basis of Inheritance for ICSE Class 12 Biology board exam 2026. MCQs, short answer, and long answer questions with marks.

60 questions36 flashcards

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A flowchart illustrating the sequential steps involved in DNA fingerprinting (DNA profiling), from DNA isolation to the detection of hybridized DNA fragments, including restriction digestion, gel elec
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60 Questions·
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Sample Questions

1mcq

Who proposed the double helix model of DNA?

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Watson and Crick

Watson and Crick proposed the double helix model in 1953, based on X-ray crystallography data from Rosalind Franklin and Maurice Wilkins. They shared the Nobel Prize in 1962.

2mcq

In DNA, which base pairs with Adenine?

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Thymine

In DNA, Adenine pairs with Thymine via 2 hydrogen bonds (A≡T). Guanine pairs with Cytosine via 3 hydrogen bonds (G≡C). In RNA, Uracil replaces Thymine.

3mcq

DNA replication in living organisms is:

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Semiconservative

DNA replication is semiconservative — each new double helix contains one original parental strand and one newly synthesised strand. This was proved by Meselson and Stahl (1958).

4mcq

What is the central dogma of molecular biology?

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DNA → RNA → Protein

The central dogma states: DNA is transcribed to mRNA, which is translated into protein. Information flows from DNA to RNA to protein.

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Frequently Asked Questions

What are the important topics in Molecular Basis of Inheritance for ICSE Class 12 Biology?
Key topics in Molecular Basis of Inheritance include DNA as Genetic Material — Key Experiments, Meselson-Stahl Experiment, DNA Structure Key Numbers. These are the concepts ICSE Class 12 examiners draw on most — study them first, then practise related questions.
How to score full marks in Molecular Basis of Inheritance — ICSE Class 12 Biology?
Understand the core concepts first, then work through the 60 practice questions available for this chapter. Revise formulas and definitions regularly, and use flashcards for quick recall before the exam.
How many important questions are there in Molecular Basis of Inheritance?
There are 60 practice questions available for Molecular Basis of Inheritance. These cover multiple question types including MCQs, short answer, and long answer questions.

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