Human Health and Diseases
Maharashtra Board · Class 12 · Biology
Complete topic list for Human Health and Diseases in Maharashtra Board Class 12 Biology. Key concepts, sub-topics, and what to focus on for board exams.
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Topics in Human Health and Diseases
Immunity and Immune System
- Immunity is the resistance exhibited by host towards injury caused by pathogens and their products
- Immune system distinguishes between self (body's own cells) and non-self (foreign molecules)
- Antigens are foreign substances that stimulate immune response; Antibodies are protective chemicals produced against antigens
Antibody Structure and Function
- Antibodies are Y-shaped glycoprotein molecules also called Immunoglobulins (Igs)
- Structure: 4 polypeptide chains - 2 heavy chains and 2 light chains held by disulfide bonds
- Variable regions form antigen-binding sites (paratopes) - provide specificity
Blood Groups and Compatibility
- ABO blood groups discovered by Karl Landsteiner (1900) - Nobel Prize winner
- Four blood groups: A, B, AB, O based on presence/absence of A and B antigens on RBCs
- Blood group A: Antigen A on RBCs, antibody b in plasma
Common Infectious Diseases
- Malaria: Caused by Plasmodium (P. vivax, P. ovale, P. malariae, P. falciparum), transmitted by female Anopheles mosquito
- Malaria symptoms: Cyclic fever, chills, sweating, headache, anaemia, hepatomegaly
- Amoebiasis: Caused by Entamoeba histolytica, transmitted through faeco-oral route
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