Microbes in Human Welfare
Tamil Nadu Board · Class 12 · Zoology
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Alexander Fleming discovered penicillin while working on Staphylococci bacteria. Which of the following correctly describes the mechanism of action of penicillin?
Cyclosporin A is an important bioactive molecule used in medicine. Which of the following statements about Cyclosporin A is CORRECT?
In the production of Swiss cheese, large holes are characteristically formed. Which microorganism is responsible for this and what causes these holes?
Streptokinase is used medically as a 'clot buster'. Which of the following correctly identifies its source and application?
Sample Questions
Ideonella sakaiensis is a recently identified bacterium with significant biotechnological importance. What makes it unique in the context of bioremediation?
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It breaks down PET plastics into terephthalic acid and ethylene glycol using PETase and MHETase enzymes
Step 1: Plastic pollution is a major environmental concern. PET (polyethylene terephthalate) is one of the most common plastics used in bottles and packaging. Step 2: Ideonella sakaiensis was identified as a bacterium capable of breaking down PET plastic, making it valuable for bioremediation. Step 3: It uses two specific enzymes – PETase (breaks PET into MHET) and MHETase (breaks MHET into simpler monomers) – to convert PET into terephthalic acid and ethylene glycol, which can be recycled. Step 4: Option A describes Pestalotiopsis microspora, a fungus that degrades polyurethane. Option C is i
A student studying biogas production learns that anaerobic digestion occurs in three sequential stages inside the digester. Which of the following correctly lists these three stages in the RIGHT ORDER?
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Solubilisation → Acidogenesis → Methanogenesis
Step 1: In a biogas plant, organic matter undergoes anaerobic digestion in a specific sequence of three stages. Step 2: Stage 1 – Solubilisation: Complex organic molecules (carbohydrates, proteins, fats) are broken down into simpler soluble compounds by hydrolytic bacteria. Step 3: Stage 2 – Acidogenesis: The simpler compounds are further broken down into organic acids (acetic acid, propionic acid) and alcohols by acidogenic bacteria. Step 4: Stage 3 – Methanogenesis: Methanogenic bacteria (like Methanobacterium) convert the organic acids into methane (CH₄) and carbon dioxide (CO₂), which cons
Which of the following CORRECTLY pairs the organic acid with the microorganism responsible for its commercial production?
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Citric acid – Aspergillus niger; Butyric acid – Clostridium butyricum
Step 1: Many organic acids are commercially produced using specific microorganisms. Step 2: The correct pairings from the chapter are: Citric acid → Aspergillus niger (a fungus), Acetic acid → Acetobacter aceti (a bacterium), Fumaric acid → Rhizopus oryzae (a fungus), Butyric acid → Clostridium butyricum (a bacterium), Lactic acid → Lactobacillus (a bacterium). Step 3: Option A is wrong because it swaps Rhizopus oryzae (fumaric acid) with Aspergillus niger (citric acid). Step 4: Option B is wrong – acetic acid is produced by Acetobacter aceti, not Lactobacillus, and butyric acid is by Clostrid
Selman Waksman was the first person to use the term 'antibiotic' in 1943. Which antibiotic did he discover, and from which organism was it isolated?
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Streptomycin, isolated from Streptomyces griseus
Step 1: Selman Waksman was a soil microbiologist who coined the term 'antibiotic' in 1943. Step 2: He discovered streptomycin, which was isolated from the actinomycetes bacterium Streptomyces griseus. Step 3: Streptomycin is a broad-spectrum, bactericidal antibiotic effective against both gram-positive and gram-negative bacteria, especially Mycobacterium tuberculosis (which causes TB). Step 4: Option A is wrong – penicillin was discovered by Alexander Fleming from Penicillium fungi, not by Waksman. Option C is wrong – tetracycline (chlortetracycline) was isolated from Streptomyces aureofaciens
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