Principles of Inheritance and Variation
ICSE · Class 12 · Biology
Complete topic list for Principles of Inheritance and Variation in ICSE Class 12 Biology. Key concepts, sub-topics, and what to focus on for board exams.
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- Law of Segregation (Purity of Gametes): alleles separate during gamete formation — each gamete carries only one allele
- Law of Independent Assortment: alleles of different genes assort independently (applies to genes on different chromosomes)
- Monohybrid F2 ratio: 3:1 (phenotypic); 1:2:1 (genotypic)
- Complete dominance: one allele completely masks the other
- Incomplete dominance (blending): F1 is intermediate — e.g., Mirabilis jalapa: RR=red, Rr=pink, rr=white; F2 ratio 1:2:1
- Codominance: both alleles expressed equally — e.g., ABO blood groups, IAIB = blood group AB
- Sutton and Boveri: genes are on chromosomes (Chromosomal Theory of Inheritance)
- Morgan: used Drosophila melanogaster — 4 chromosomes, short life cycle, easy to culture
- Linkage: genes on the same chromosome tend to be inherited together
- Humans: XX (female), XY (male) — father determines sex of offspring
- Birds: ZW (female), ZZ (male) — mother determines sex
- Grasshopper: XX (female), XO (male) — no Y chromosome
Chapter Syllabus
Principles of Inheritance and Variation is part of the ICSE Class 12 Biology syllabus. It covers the core concepts and topics prescribed by the board for the 2026 academic year.
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