Genome Technology and Engineering

The genome of an organism refers

The genome of an organism refers to the complete genetic information present in its cells. In prokaryotes, it includes DNA present in the nucleoid reg

Genetic mapping estimates the relative distances

Genetic mapping estimates the relative distances between two or more genetic loci by analysing the frequency of crossover (recombination) between them

Physical mapping identifies specific locations on

Physical mapping identifies specific locations on the genome using DNA-based features. Three major types are: (1) Restriction Fragment Length Polymorp

The first generation sequencing technique

The first generation sequencing technique, also called chain termination sequencing (Sanger sequencing), involves creating a ladder of single-stranded

NGS uses massively parallel sequencing

NGS uses massively parallel sequencing — millions of reactions simultaneously — to dramatically reduce cost and time. Illumina sequencing, the most po